![]() Grade 1 and 2 memory impairment (26 of 86 v seven of 88 patients) and cognitive disturbance (16 of 86 v three of 88 patients) were significantly increased in the PCI arm. Overall survival was not significantly different between both arms. Median time to develop brain metastases was not reached in either arm. PCI significantly increased the time to develop symptomatic brain metastases (hazard ratio, 0.23 P =. Six (7.0%) of 86 patients in the PCI group and 24 (27.2%) of 88 patients in the control group had symptomatic brain metastases (P =. Median follow-up was 48.5 months (95% CI, 39 to 54 months). ![]() Results Between 20, 175 patients were randomly assigned: 87 received PCI and 88 underwent observation only. Adverse effects, survival, quality of life, quality-adjusted survival, and health care costs were secondary end points. The primary end point-development of symptomatic brain metastases at 24 months-was defined as one or a combination of key symptoms that suggest brain metastases-signs of increased intracranial pressure, headache, nausea and vomiting, cognitive or affective disturbances, seizures, and focal neurologic symptoms-and magnetic resonance imaging or computed tomography demonstrating the existence of brain metastasis. read more magnetic resonance imaging-were randomly assigned to either observation or PCI after concurrent/sequential chemoradiotherapy with or without surgery. ![]() Patients and Methods Patients with stage III NSCLC-staged with a contrast-enhanced brain computed tomography or. But I’d rather have the functionality in place I describe in the prior paragraph.Purpose The purpose of the current study was to investigate whether prophylactic cranial irradiation (PCI) reduces the incidence of symptomatic brain metastases in patients with stage III non–small-cell lung cancer (NSCLC) treated with curative intention. If I index that folder per the recommendation above, then I get the notes that are in it. So then I saved another new note to a different folder and then moved it into that folder. Then I created a test note in TextEdit and saved it to that folder. But then I had an idea, I tried creating a new folder on my desktop simply for notes to be imported into DTPO, and set up folder services on it per above. If I drag a pdf to that folder, that gets imported into DTPO as expected. I put that in place on the nvALT folder and when I create a new note, nothing. I’m having hit or miss success with this functionality. Then I have a folder where when I save a document into it or move one into it, it invokes the folder services action of importing it into DTPO, runs OCR and deletes it from the original folder. I tried indexing the folder and it shows the folder and the container for the notes but doesn’t show any of the notes. it appears that nvALT saves them in its own container, each note is not identified as a separate file, and thus far I’m not having any success getting those notes into DTPO. Here’s what I’d love to get put in place:įirst, I find a markdown-enabled text editor that saves simple text files to a user-specified folder. Again, would love to be able to hit a hotkey, start typing, and then with one or two more keystrokes share with DTPO and get back to work. Was hoping maybe nvAlt would work but I can’t find a simple way to share a new note with DTPO. I’m trying to find some analogous workflow on my Mac. On my iPhone, I can just launch Drafts, type a note, share it to DTTG and get back to work. I need to find a way to add such notes as quickly and efficiently as possible with as little interruption to my work as possible. Sometimes in the middle of doing one thing an idea occurs to me and I want to capture it in DTPO, but right now the “transactional friction” is a problem. There I could hit a hotkey, it would bring up a text entry window, I just start typing, save and I’m done. Seems this is one more thing I’m missing in my transition from Evernote. Looks like if I want to add a text note I have to actually leave the app I’m in, go to DevonThink, I can then hit the appropriate hotkey (and I wish the app would let me re-map hotkeys to avoid conflicts with other apps, this is one of the few apps that doesn’t permit that), and that then actually puts me into the title field and makes me type a title, THEN I can click over to the text field and start typing. I’m trying to figure out quick and easy ways to add text notes on the fly and I’m not seeing anything.
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